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Suppression of the malignant phenotype in pancreatic cancer by the overexpression of phospholipid hydroperoxide glutathione peroxidase (PhGPx)

Rosenfeld SV, Togo EF, Mikheev VS, Popovich IG, Khavinson VKh, Anisimov VN

Additionally, these systems retain useful performance in elevated-temperature environments, making them well-suited for applications such as heat shields, friction materials, ducts, panels, and insulation-facing components

Thiram-induced cytotoxicity is accompanied by a rapid and drastic oxidation of reduced glutathione with consecutive lipid peroxidation and cell death

doi: 10.1038/npp.2017.160

Next, we validated the network with bulk transcriptional data, single-cell transcriptional data and epigenetic data using kidney tissue from independent human cohorts