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10.1161/HYPERTENSIONAHA.107.108944 153

PMID 8605177

IGF-1 LR3 IGF-1 LR3 is a modified recombinant insulin-like growth factor 1 analogue of 83 amino acids synthesised with an N-terminal extension and Arg3 substitution, studied in anabolic signalling research for its role in increasing the free fraction of circulating IGF-1 (~3 vs native)

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This combination represents the most widely studied GH secretagogue pairing, based on the well-characterized synergistic interaction between GHRH and GHSR signaling at the pituitary level

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