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Yoshioka S, Hamada A, Jobu K et al (2010) Effects of Eriobotrya japonica seed extract on oxidative stress in rats with non-alcoholic steatohepatitis

The first cardiovascular study of NNMT enzyme inhibition in a heart failure with preserved ejection fraction (HFpEF) mouse model demonstrated that treatment markedly reduced 1-MNA (by 77.1%), 2PY (by 66.2%), and 4PY (by 71.1%) in cardiac tissue, while improving cardiac function, enhancing global longitudinal strain, reversing peak longitudinal strain rate, and significantly reducing left ventricular hypertrophy and fibrosis

SiMYB3 could specifically bind to the MYB element in the promoter region of the TAR2 promoter region of the growth hormone synthesis-related genes conserved in Oryza sativa and Setaria italica

Hepatology 42 , 11481157 (2005)