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Experimental protocols for all animals were approved by the Ethical Committee of Xiangya Hospital Central South University

Then we discussed the adverse effect of GH-IGF1 signaling in radiotherapy to cancer cells and the favorable impact of GH-IGF1 signaling on radiation damage repair to adjacent tissues after irradiation

Hence, in general, the stability of formyl- and/or oxidized forms is much higher than that of methyl- and/or reduced ones, and the acidic environment accelerates the thermal decomposition 66,106,234,346,363,364,365,366,367,368,369,370,371,372,373,374

Additional Phase 3 trials are still underway, including TRIUMPH-2 (evaluating retatrutide in adults with obesity and type 2 diabetes) and TRIUMPH-3 (evaluating cardiovascular outcomes), with results expected later in 2026

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