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Neuroimmune dysregulation is central Disrupted immunenervous system communication likely played a key role

This anti-inflammatory activity occurs without apparent immunosuppression, suggesting selective modulation of inflammatory pathways rather than global immune suppression

not statistically significant [6]

Acetate, predominantly synthesized by Bifidobacterium , plays a pivotal role in preserving the functionality of the intestinal epithelial barrier and modulating intestinal inflammation through the activation of the G protein receptor (GPR) 43 (Yoo et al., 2020)

10.1111/ene.14190 82 MasroriP.Van DammeP

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