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Moreover, MitoQ appears to have a stronger inhibitory effect on cells with higher MYCN levels, similar to that observed with DPI (16)

Further studies revealed that DAA was able to bind to Keap1 in the cytoplasm and increase the luciferase activity of Nrf2-antioxidant reactive element (ARE), promoting the expression of downstream antioxidant gene hame oxygenase-1 (HO-1), GSH, and GPx4 through the Keap1/Nrf2 pathway, while DAA treatment results in achieving attenuation of ROS and lipid peroxidation ( 2+ , which is manifested as an inhibition of ferroptosis (66)

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Lewis 1984;Yoshitomi, Alison, and Boorman 1986

a.: L-Carnitine-supplementation in advanced pancreatic cancer (CARPAN)--a randomized multicentre trial In: Nutrition Journal

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