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157,158,159,160,161,162 The effect of PARPs to stimulate chromatin decompaction might be exerted via the steric hindrance of PAR chain, the negative charge of DNA and PAR, or the displacement of core histones

Tirzepatide remains an important model for understanding dual incretin signaling

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That matters on GLP-1s because fullness can arrive quickly, and one or two extra handfuls may be the difference between feeling fine and feeling nauseated

Ethics declarations Competing interests The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper