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However, serum acylcarnitine levels did not significantly increase in the L-carnitine group

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This decline creates several problems: Low NAD+ leads to reduced DNA repair capacity and more DNA damage Decreased NAD+ hurts mitochondrial fatty acid -oxidation and oxidative phosphorylation NAD+ depletion affects all hallmarks of aging The good news is that restoring NAD+ has shown great results in preclinical studies

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doi: 10.3390/jcm13195698 109 MitroviM.Stankovi-PopoviV.TolinakiM.GoliN.BajiS