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5-Amino-1MQ selectively inhibits nicotinamide N-methyltransferase (NNMT), a methyltransferase enzyme that catalyzes the transfer of a methyl group from S-adenosylmethionine (SAM) to nicotinamide, producing 1-methylnicotinamide

Non-B12 causes of persistent symptoms with a high result When symptoms persist and the B12 is high, the symptoms may have nothing to do with B12 at all

Some researchers have studied vitamin B12 to find out if it can increase energy and endurance during exercise, but the results are inconclusive

By blocking NNMT, 5-amino-1MQ stimulates an increase in nicotinamide adenine dinucleotide (NAD+), a cofactor that is central to cellular metabolism, thereby increasing metabolic rate and activating a gene called sirtuin-1 (SIRT1)

Better Health Digestion B12 is essential for a healthy digestive system because it helps the body make stomach acid and break down food

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