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Diabetes, Obesity and Metabolism, 24 (8), 1553-1564

The authors concluded that obesity behaves like a chronic condition, and that ongoing treatment is generally needed to maintain the improvements in weight and health

External eating is the tendency to eat in response to external cues, such as sights, smells, or the availability of food, rather than to internal feelings of hunger or fullness

NHS availability is unlikely before the mid-to-late 2020s at the earliest, as retatrutide must first complete phase 3 trials, receive MHRA marketing authorisation, and undergo a NICE health technology appraisal to assess its clinical and cost-effectiveness

Individual tolerance often determines optimal dosing, with some users finding 8mg provides excellent results with fewer side effects while others tolerate and benefit from 12mg dosing

If lifestyle changes havent led to sufficient weight loss, your doctor may recommend using one of these medications in conjunction with healthy eating and regular exercise