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A treatment plan should also take into account that many of these patients will have underlying derangements in their autoimmune system that the COVID-19 infection is just unmasking, she said, noting that investigations into the role of mitochondrial dysfunction, which could explain why untreated POTS sometimes evolves into chronic fatigue syndrome, are ongoing
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PMID 10318826
But certain situations may require skipping a dose or timing adjustments
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