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As time progresses, having low levels of BDNF can negatively impact on the brains ability to build and repair itself

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Tirzepatide for T2D obesity SURMOUNT-2, weight -12.8/-14.7% at 10/15 mg, attenuated about 6-7 points vs non-diabetic obesity: Garvey Lancet 2023

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This guide examines the science behind each peptide, compares their clinical applications, and provides practical guidance for anyone considering peptide therapy

Much of this evidence comes from preclinical models, so human conclusions remain limited