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A lack of intracellular cysteine, GSH, or SLC7A11 suppression reduces GPX4 activity, which can enhance lipid peroxidation and trigger ferroptosis (47)

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Notably, MG can also affect the expression of tumor cell-associated immune proteins, thereby interfering with anti-tumor immune effects

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Waldner, R., Laschan, C., Lohninger, A., Gessner, M., Tuchler, H., Huemer, M., Spiegel, W., and Karlic, H