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Stopping GLP-1 medications suddenly can throw your body off balance, disrupting its ability to manage hormones and blood sugar effectively

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26,27 A Phase II trial in T2D showed a 1% reduction in HbA1c (Diabetes Control and Complications Trial units) and approximately 1.7% body weight reduction over 12 weeks, in comparison to placebo, but a further comparison to an open-label liraglutide active treatment control group was less impressive

ABSTRACT KEY FIGURE Highlights The DEVELOPMENT AND USE OF GLUCAGON-LIKE PEPTIDE-1 STRUCTURE, DISTRIBUTION, AND PHYSIOLOGICAL FUNCTION OF GLP-1 GLP-1 MODULATES LIPID METABOLISM CLINICAL APPLICATION OF GLP-1 IN LIPID METABOLISM AND ADIPOSE-RELATED DISORDERS GLP-1 AND DUAL AGONISTS CONCLUSIONS NOTES REFERENCES About this article ABSTRACT Glucagon-like peptide-1 (GLP-1) is a 30-amino acid peptide hormone that is mainly expressed in the intestine and hypothalamus