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While it is generally considered safe, it is essential to consult with a healthcare provider before starting any new supplementation regimen
R.FarokhniaM.YadegariN.TabriziM.et al
Aging Cell 12 , 148155, (2013)
However, there is no scientific consensus supporting its efficacy or safety when used in this way
A phase 4 trial (NCT04522739) was started in September 2022 to investigate whether spironolactone can be tolerated by older Black American adults with MCI and to determine its effect on memory and thinking abilities, as measured by participant performance on cognitive tests
For most people, daily oral methylcobalamin is more practical than chasing B12 energy shots, which are really designed for confirmed deficiency or malabsorption
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