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Its also interesting to note that most of the detoxing done by glutathione is occurring in the two most metabolically active organs in human physiologythe liver and the brainas these two organs generate and utilize more glutathione than any other organs

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This finding accounts for the important observation that the c-met binding affinity of LASSS/peroxynitrite-treated HGF (at the 1:8000:2000 molar ratio to HGF, with the wash-out of un-reacted free LASSS) was significantly higher than the original level of un-treated positive control HGF (Figure 2d, bars 2 and 6 )