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MT-2 produces minimal gastrointestinal side effects because it doesnt delay digestion, while GLP-1 agonists cause nausea in 3045% of users during dose escalation

In fact, patients who experience some initial nausea often show stronger weight loss outcomes because the medication is effectively activating appetite-suppressing pathways

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A completely different approach was employed by He et al

Youll likely be given specific instructions on how and where to inject it, typically in the abdomen, thigh, or upper arm

Fujimoto WY (2000) The importance of insulin resistance in the pathogenesis of type 2 diabetes mellitus