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In terms of side effects and tolerability, the advantage goes to Afamelanotide
A catch-up rate was applied after treatment cessation to bring the values of the treatment efficacy on the risk factor endpoints back to their baseline values or to a value on their progression with D&E, depending on whether the cohort remains on D&E (Supplementary Table S3)
Most evidence for how BPC-157 works comes from rodent models, where it appears to promote the bodys natural repair mechanisms
In the present study, an increase in ROS content was also observed in cells exposed to 6-OHDA, which is similar to other findings in this field (39)