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Some patients report mild nausea or gastrointestinal effects during peak days, which typically resolve quickly as levels begin to decline
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Interest in Zepbound self-pay and off-label applications like Zepbound for sleep apnea highlights both cost concerns and exploratory uses
In clinical trials, semaglutide has demonstrated superior weight loss compared to older GLP-1 analogs, with an average loss of 15-20% of body weight
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