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Its main mechanism of action would be its ability to bind to serum calcium, preventing activation of the coagulation cascade and prolonging the time till blood clot formation

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These are modest compared to pharmaceutical options

These immune-restorative effects are believed to work synergistically with the peptide's telomerase activation to slow immunosenescence

Methods In a multicentre, double-blind clinical trial, we randomly assigned patients with type 2 diabetes or obesity to intravenous tocilizumab (an IL-6 receptor antagonist) 8 mg/kg every 4 weeks, oral sitagliptin (a dipeptidyl peptidase-4 inhibitor) 100 mg daily or double placebos (a placebo saline infusion every 4 weeks and a placebo pill once daily) during a 12 week training intervention