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The small but significant increase in people with low blood pressure and with kidney stones are likely attributable to the fact that a combination of diarrhoea and reduced oral intake can lead some people to become somewhat fluid-depleted

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According to FDA prescribing information, gastrointestinal side effects are typically mild to moderate in severity and tend to diminish over time as patients develop tolerance to the medication

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In a 2014 study, researchers found that older adults who participated in regular physical activity had higher levels of glutathione