Los asignados a semaglutida perdieron una media de 15,3 kg frente a 2,6 kg con placebo (diferencia de tratamiento estimada, 12,7 kg
reported that GLP-1RAs can promote the overactivation of GLP-1R in pancreatic cells, which not only increases susceptibility to pancreatic inflammation but also increases the risk of pancreatic cancer
They may include: Mild nausea, vomiting, or diarrhea Constipation Abdominal pain or discomfort Headache These effects are usually short-lived and can often be minimized by ensuring you are well-hydrated, by adjusting your diet (e.g., avoiding fatty foods, eating smaller meals), and by gradually increasing your dose as advised by your provider
Monitor Blood Sugar : If you have diabetes, closely monitor your blood sugar levels, especially when starting the medication, to avoid hypoglycemia
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[PubMed] [Google Scholar] 33.Yip L, Dart RC, Hurlbut KM