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In the Lancet diabetes trial, seven of 403 people on the drug had arrhythmias and three had major cardiovascular events, against none on placebo

Vogt & Richie, 2017)

Oral forms exist but have lower absorption

Because of this, in 2021, the FDA approved semaglutide (Oxempic & Wegovy are the brand names) for use in obesity management

Recent genetic research has identified specific variants in the GLP1R, GIPR, MC4R, and FTO genes that influence how efficiently your body responds to GLP-1 therapy