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Increased generation of superoxide by angiotensin II in smooth muscle cells from resistance arteries of hypertensive patients: role of phospholipase D-dependent NAD(P)H oxidase-sensitive pathways

Structurally it is based on the full 44-amino-acid growth-hormone-releasing factor sequence (hGRF 1-44) with a modification that protects it from rapid enzymatic breakdown, extending its usefulness compared with native GHRH

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Lin S, Andrikopoulos S, Shi YC, et al