The antidiabetic hormone glucagon-like peptide-1 induces formation of new elastic fibers in human cardiac fibroblasts after cross-activation of IGF-IR
It does three things that drive weight loss and also explain virtually every side effect on this list: Slows gastric emptying food stays in the stomach longer nausea, reflux, bloating, Ozempic burps Suppresses appetite via the brain reduced food intake headaches, fatigue, low energy from low calories Reduces gut motility slower transit constipation
The salt forms have never been tested in clinical trials
The SELECT, STEP, and ESSENCE programs collectively support its role across this spectrum, with robust efficacy but a characteristic GLP1 RA tolerability profile that necessitates careful initiation, titration, and monitoring
Concerned about hair thinning on Ozempic, Wegovy, or Zepbound
This episode serves not only as a celebration of 100 episodes but as a masterclass in leadership, growth, and maintaining excellence in aesthetic medicine