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The theory is that smaller, more frequent doses maintain receptor stimulation at a level that avoids heavy desensitization while preserving beneficial effects

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In these cases, serum B12 levels will shoot up (the blood test counts inactive B12 too), but there may still be a deficiency of adenosyl B12 and methyl B12 in the cells, tissues and body fluids

PDRN (Polydeoxyribonucleotide): the adenosine A2A receptor agonist PDRN is a mixture of short and long DNA polymers extracted, in commercial preparations, from the gametes of salmon trout

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