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While melatonin is the primary hormone produced by the pineal gland, Epithalon is studied as a peptide regulator of pineal function that might influence melatonin production along with other pineal outputs

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Of note, the research on KPVs effects has been done primarily in animal models and human cell cultures, not in human subjects directly

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In another study, it was reported that SOD activity decreased in bladder cancer patients compared to healthy control groups 45

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