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EU approval expected 2026USEU 5assets BDC-4182BDC-4182 / Claudin 18.2 / Boltbody ISAC / OncologyGastric cancerPhase 1Ongoing dose-escalationGastroesophageal cancerPhase 1Ongoing dose-escalation BDC-3042BDC-3042 / Dectin-2 / Agonist monoclonal antibody / OncologyNon-small cell lung cancer, melanoma and other solid tumorsPhase 1Dose-escalation complete
But expectations need to stay grounded
That said, side effects can occur: Common side effects (mild and transient) Injection site reactions: Redness, mild swelling, or tenderness at injection sites
Adding glucagon receptor activity introduces a third variable, and "calling fat out of storage" sounds great until you start asking what else it might be doing to a patient's metabolism, cardiovascular system, and hormonal balance long-term