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This ERK-without-Akt profile supports cellular proliferation and survival while maintaining cells in a proliferative rather than differentiated state contrasting sharply with IGF-1s PI3K/Akt/mTOR-dominant signalling, which drives protein synthesis and differentiation

Tani, K., Mizoguchi, T., Iwamatsu, A., Hatsuzawa, K

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O., Pickholz, M., Remko, M., Saviano, M., Skwarczynski, M., Tang, Y., Wolf, W

The luminescent signal is proportional to the amount of glutathione within the sample and stable for 3 hours, allowing flexibility in data collection schemes