If confirmed in larger studies, this could influence long-term dosing strategies and improve treatment sustainability
While both medications belong to the GLP-1 family, tirzepatides dual GIP and GLP-1 mechanism introduces unique considerations during a switch
The FDA approved this drug, which was first created to treat type 2 diabetes
However, liver function should be monitored during treatment, particularly during dose escalation when the metabolic demands on the liver increase
Fitchett D, Inzucchi SE, Cannon CP, McGuire DK, Scirica BM, Johansen OE, et al
Regulation of lipoprotein lipase and hormone-sensitive lipase activity and gene expression in adipose and muscle tissue by growth hormone treatment during weight loss in obese patients