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It causes a transient rise in systolic blood pressure ($+6$ mmHg) and a slight drop in heart rate that lasts about 12 hours

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Why is individualized care important in weight loss management

Combine them with lifestyle interventions like meeting with a dietitian, eating less processed foods, and finding ways to be more physically active. People who use GLP-1s without lifestyle changes may gain weight back after stopping the medication

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doi: 10.3389/fpls.2021.816233 21 JhinganSHarloffHJAbbadiAWelschCBlmelMTasdemirDet al