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In the crystal structure of ASK1 Os D3 At D14 (PDB 5HZG), ASK1 is also retracted, and the CTH is engaged, suggesting that this conformation is caused by the presence of the SL receptor (D14/HTL7) (Supplementary Fig
Cytokine 56:256264 Mirza RE, Fang MM, Ennis WJ, Koh TJ (2013) Blocking interleukin-1beta induces a healing-associated wound macrophage phenotype and improves healing in type 2 diabetes