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Liraglutide (Saxenda): The Modest but Reliable Option Liraglutide doesn't get much attention these days because newer medications are more effective, but it deserves a mention as the original GLP-1 weight loss medication
It has passed phase 1 and 2 clinical trials and is currently in phase 3 trials, with an expected launch in 2026 or 2027 if approved
Spacing doses appropriately can minimize compound digestive upset
Months 2 to 6 : The most active weight loss phase
Gastrointestinal adjustment in the first weeks mild nausea, slower digestion, occasional reflux is also widely reported and typically settles with titration
Cochrane Database Syst Rev (2019) 8:295
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