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The anti-inflammatory action of ghrelin occurs mostly via the inhibition of the NFB pathway [240,241], and not by scavenging intracellular ROS [226] even if ghrelin has antioxidant properties [228,233,242]

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Dar found that when PA infected epithelial cells, M1-activated macrophages expressed iNOS/NO in the host immune cells, which could make the cells resistant to ferroptosis [47]

IBD, inflammatory bowel disease

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Rather than waiting passively for healing to occur, the peptide actively recruits the cellular machinery necessary for tissue regeneration