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Many of these receptors are clathrin-dependent endocytosed, one example being LRP1 which is responsible for the endocytosis of amyloid-beta and APOE 2 and 3 [12]

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In addition, newly established HLA-gliadin complexes localised to the surface of antigen presenting cells, activate T-cells to promote the release of anti-gliadin and anti-tissue transglutaminase (tTG) antibodies by B cells and plasma cells (Smyth 2017)

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The jellyfish processes are juxtaposed with one another and form a continuous barrier along the glial limitans