These opioid receptors are distributed in central and peripheral nervous systems, gastrointestinal tract, immune cells, and some other tissues
Ioannidou: [00:37:57] Well, this is a very good point
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To address the question of whether the cardioprotective actions of GLP-1(2836) require a functional transmembrane GLP-1R, we repeated these experiments using hearts isolated from mice with genetic deletion of 2 exons of the Glp1r gene (26)