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Research indicates that FOXO factors may have both protective and detrimental effects in the context of neurodegeneration, depending on how they are regulated

The potential for glucagon-like peptide 1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP) receptor agonists to impact these pathways will then be reviewed, along with preliminary clinical outcomes for repurposed drugs targeting these incretin hormones

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Moreover, studies have shown that specific Chinese medicines, including resveratrol and Xiaoyaosan, alleviate depressive symptoms by regulating multiple biological pathways