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Sterility: Produced and tested to be free from detectable microbial contamination

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Higher doses or additional medications Repeated injections without sustained improvement Increasing side effects with diminishing therapeutic return At this stage, pain is no longer simply a symptomit reflects underlying regulatory imbalance

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While peptide therapy may possess significant therapeutic and regenerative potential, it is critical that orthopedic and sports medicine providers understand the current lack of evidence to support the clinical use of these peptides, the authors concluded