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As of the latest WADA update, BPC-157 is not listed on the WADA Prohibited List

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The absence of trial data on the combination means any interaction would have to be inferred from theory rather than evidence

This rate of loss creates significant metabolic stress

Endotoxin testing results should also be available

Caution is advised in patients with Leber optic atrophy, a genetic disorder caused by chronic cyanide intoxication (such as from smoking, alcohol or some plants), against the use of cyano-B12 due to its cyanide moiety, whilst hydroxo-B12 is a cyanide antagonist and can therefore be used in these patients