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Akkermansia lives in the mucus layer of the gut lining

And these drugswhile new, expensive, and with downsidesdo appear to help some people, like Paul Ford, who shared his experience with Mounjaro in Wired, and Ron Passmore, who spoke with Slate

This contributes to reductions in body fat percentage over time

It belongs to a class of drugs called anorectics (medications that reduce appetite) and is classified by the United States Drug Enforcement Administration (DEA) as a Schedule IV controlled substance, meaning it has recognized medical use but also some potential for dependence

Most side effects are manageable with appropriate support, and the benefits of improved glycaemic control typically outweigh the risks for appropriately selected patients