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Deep sequencing in microdissected renal tubules identifies nephron segment-specific transcriptomes

Properly reconstituted IGF-1 LR3 dissolves completely within 2 minutes without agitation when water is added slowly down the vial wall rather than directly onto the lyophilised powder

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These disruptions lead to water and sodium influx, potassium efflux, cell swelling, membrane potential changes, and eventual cell lysis, which then releases intracellular contents, eliciting an inflammatory phenotype through DAMP release and triggering immune responses (Murao et al., 2021)