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Alternatively, acetylcarnitine, produced in excess in mitochondria by CrAT, is transported into cytosol by CACT and enters the nucleus, where a nuclear CrAT converts the acetylcarnitine to acetyl-CoA 67 , and it becomes a source of acetyl groups for histone acetylation

These include chest pain or tightness, severe headaches, palpitations or irregular heartbeat, difficulty breathing, severe dizziness or fainting, or sudden vision changes

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