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In vivo, HPV infection requires initial association of virus with an acellular basement membrane, and it was shown that antibodies to L1, the major capsid protein of HPV, can interfere with infection at two stages

These authors make the point that genetic effects often appear to be greater in males, perhaps related to their tendency to higher UA concentrations

10Witschi A, Reddy S, Stofer B, Lauterburg BH

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Chemical modifications of nucleic acid drugs and their delivery systems for gene-based therapy

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