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Family 2: GHRP and ghrelin mimetics (ghrelin pathway) GHRPs (Growth Hormone Releasing Peptides) act on a completely separate receptor: GHS-R1a , identical to the endogenous ghrelin receptor

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Treatment with exenatide has been shown to decrease food intake and attenuate food-related neural responses in key regions such as the insula, amygdala, putamen, and orbitofrontal cortex (van Bloemendaal et al., 2014)

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