glutathione excess Changes in levels of the antioxidant in brain and blood across the age span of healthy adults: A systematic review 9 Health Benefits of Glutathione

This leads to a lot of wasted money and lower efficacy of treatment

No adverse effect on fertility was observed at 50 mg/kg/day (systemic exposures up to 10 times the human exposure at 40 mg/day based on AUC)

After attaining the desired skin color, a maintenance dose of 500 mg per day for a longer duration is suggested

It's a carotenoid

It helps regulate blood flow, vascular tone, inflammation, and clotting

These results suggest that upon depletion of GSH, tissues undergo reprogramming to hyperactivate NRF2, possibly as a mechanism to upregulate adjacent antioxidant pathways and buffer oxidative stress induced upon GSH depletion