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Journal of Chromatography A, 1265, 57-69

Step Four: Calculate the Market-based Relative Weights: For each MS-DRG, the market-based relative weight would be calculated as the ratio of the single weighted average standardized median MAO payer-specific negotiated charge for that MS-DRG across hospitals from Step Two to the single national weighted average standardized median MAO payer-specific negotiated charge across all MS-DRGs from Step Three

This finding is important for developing effective anti-doping tests, as its often the metabolites of a substance, rather than the substance itself, that are detected in biological samples

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