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It is needed for the metabolism of fats and helps to keep cholesterol levels under control

IGF-1 LR3 binds to IGF receptors, particularly type-1 IGF receptors, to exert its biological effects within these complex signaling pathways

References Teichman, Steven L., et al

University of Tokyo Press

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Immunobiol 214:339 Martin D, Rojo AI, Salinas M, Diaz R, Gallardo G, Alam J, De Galarreta CM, Cuadrado A (2004) Regulation of heme oxygenase-1 expression through the phosphatidylinositol 3-kinase/Akt pathway and the Nrf2 transcription factor in response to the antioxidant phytochemical carnosol