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The efficacy estimand, predefined in the statistical analysis plan, estimates the treatment effect of aleniglipron relative to placebo at week 36 in participants who met the inclusion criteria and would have completed the treatment period

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In fact, the prediction of ASD pathogenesis risk could reach 90% accuracy based on trans-sulphuration and trans-methylation metabolites, such as GSH, that are collected during the third trimester [188]

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