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SO is projected to affect up to 200 million individuals over the next 35 years, underscoring its potential as an increasingly important public health issue [4]

Over time, chronic inflammation can persist behind a repaired BBB, especially in progressive MS, but the initial establishment of neuroinflammation requires BBB disruption and infiltration

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1 NAFLD is most commonly diagnosed in overweight and obese individuals, particularly those with metabolic syndromes including type 2 diabetes (T2D) and dyslipidemia