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Together, these changes mean that a much higher fraction of administered IGF-1 LR3 reaches tissue receptors as free ligand compared to an equivalent molar dose of native IGF-1

Ethics statement The approval for this study was obtained from the Human Research Ethics Committee of the University of New South Wales (human brain tissue reference number HC12563)

If a small amount of medication leaks from the injection site or you notice bleeding, apply gentle pressure with a clean tissue

Intranasal bioavailability for Semax is estimated at 60-80% based on pharmacokinetic modeling

Both delivery methods work

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